SimSearch is a pattern-search algorithm that provides biologists with the ability, once they identify an interesting genomic pattern, to look for similar occurrences in the data, thus facilitating genomic data access and use.
For example, such patterns can describe gene expression regulatory DNA areas including heterogeneous (epi)genomic features (e.g. histone modification and/or different transcription factor binding regions).
It is possible to define complex patterns based on perfect matching in genome tracks (regions that must match), partial matching (regions that are allowed to be absent), and negative matching (for instance to search for regions distant from transcription start sites).
- Example: Distal enhancer
SimSearch is part of the DATA-DRIVEN GENOMIC COMPUTING (GeCo) project.
The SimSearch IGB App and its documentation are freely available for non-commercial use.